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Applications Invited for LCRF Leading Edge Research Grant Program 2025
![Applications Invited for LCRF Leading Edge Research Grant Program 2025](./grants/grant_logo/67a5e429a8269.png)
Organization: Lung Cancer Research Foundation (LCRF)
Apply By: 03 Mar 2025
Grant Amount: 150000 USD
About the Organization
The Lung Cancer Research Foundation has evolved over the years, but one thing remains the same. We are determined to create a world without lung cancer. Together, we can accomplish more than any one of us can alone.
The mission of the Lung Cancer Research Foundation (LCRF) is to improve lung cancer outcomes by funding research for the prevention, diagnosis, treatment and cure of lung cancer.
About the Grant
Lung cancer continues to be the number one cause of cancer deaths in the United States and worldwide, accounting for an estimated 125,070 deaths annually in the United States alone1 . When detected at an early stage (Stage I), the prognosis is good for most patients. The current standard for detecting lung cancer is low dose computed tomography (LDCT), with follow-up confirmation via biopsy. The U.S. Preventive Services Task Force (USPSTF) updated its recommendations in 20212 to include annual LDCT screening for patients who are 50-80 years of age, have a 20 pack-year smoking history, and are either a current smoker or have quit within the past 15 years. While this has increased the number of people eligible for screening, it is still limited to people with a smoking history. Given the significance of and need for early detection of lung cancer and advancements in molecular screening, LCRF continues this mechanism to support research projects that facilitate prevention or approaches for early detection of lung cancer. Work supported through this mechanism addresses important questions in non-small cell and small cell lung cancer.
This funding mechanism is focused on identifying, characterizing, and developing approaches and techniques that will allow early detection and/or prevention of lung cancer and gaining insight into pre-neoplastic processes in the lungs. The ultimate goal is to detect lung cancer at the earliest stages and subsequently increase survival and survivorship. While this list is not exclusive, general areas of interest include:
- Improvements in risk stratification of patients and uptake for screening
- Identification and characterization of new biomarkers for NSCLC and SCLC
- Development of predictive, diagnostic, or prognostic biomarkers
- Liquid biopsy assays and related techniques
- Genomic and histological approaches to improve early detection in tissue samples
- Novel imaging and computational modalities to identify and risk stratify pre-neoplastic lesions
- Implementation science with systematic uptake of evidence-based research findings into routine practices to improve quality and effectiveness of health services for early detection
- Studies of pre-neoplasia and progression to lung neoplasia to inform prevention strategies
- Development of pathways to increase uptake and utilization of lung cancer screening
- Epidemiology studies to identify risk factors and implementation of prevention measures
- Development of any new technologies that will aid in identifying early-stage lung cancers
Grant size
The maximum award amount is $150,000 for a period of two years (disbursed at $75,000 per year).
Eligibility
Investigators must be affiliated with a non-profit academic or research institution and must be post-doctoral researchers, clinical fellows, or early-career and mid-career investigators with less than ten years’ experience since their initial faculty appointment. Applicants from US-based and international institutions are eligible to apply and may hold any residency/citizenship status.
Applicants are prohibited from applying if they have received funding from the LCRF within the last 4 years. Applicants are prohibited from applying in more than one of LCRF’s funding tracks in the same cycle. Senior investigators with more than ten years’ experience since faculty appointment are generally not eligible for funding and are encouraged to mentor a junior team member through the application process. However, exceptions will be made for investigators with more than ten years’ experience in other disease areas or topics. Ineligible investigators with these or other special circumstances may request review by contacting the LCRF grants office (see Inquiries section below) before submitting an application and at least a week before submission deadline. Ineligible applications and new requests under special circumstances will not be considered after submission deadline.
How to Apply
LOI submission deadline is March 3, 2025. Applicants will be notified of their status on April 18, 2025, and the full proposal submission deadline is June 2, 2025.
For more information please check the Link
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